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A phase I clinical and pharmacokinetic study of paclitaxel and docetaxel given in combination in patients with solid tumours

✍ Scribed by Miguel Angel Izquierdo; Margarita García; José Luis Pontón; Marisa Martínez; Vicente Valentí; Matilde Navarro; Miguel Gil; Felipe Cardenal; Ricard Mesía; Xavier Pérez; Ramón Salazar; Josep Ramón Germà-Lluch


Book ID
116428816
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
142 KB
Volume
42
Category
Article
ISSN
0959-8049

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Phase I clinical trial of weekly combine
✍ Jacob Lokich 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB 👁 2 views

A Phase I and feasibility study of combined docetaxel (D) plus paclitaxel (P) was undertaken to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) for each analogue delivered concomitantly on a weekly schedule. ## METHODS. Patients were accrued in 3-6 patient cohorts to P