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A Pharmacokinetic Model for Predicting Absorption, Elimination, and Tissue Burden of Toxaphene in Rats

โœ Scribed by Yuan Hua Wen; Hing Man Chan


Book ID
112267244
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
90 KB
Volume
168
Category
Article
ISSN
0041-008X

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a two-step protonation. As a check of the method, the pKa of o-iodobenzoic acid was determined concurrently, yielding the value of -7.4 which is in good agreement with previously published data ( 12). A first protonation of compound I could lead to structures Ib, Id, Ic, or If; loss of water from I