Pharmacokinetic model for nalidixic acid
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G. A. Portmann; E. W. McChesney; H. Stander; W. E. Moore
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Article
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1966
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John Wiley and Sons
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English
โ 532 KB
a two-step protonation. As a check of the method, the pKa of o-iodobenzoic acid was determined concurrently, yielding the value of -7.4 which is in good agreement with previously published data ( 12). A first protonation of compound I could lead to structures Ib, Id, Ic, or If; loss of water from I