Aldol reaction of aldehydes with difluomketene ethyl trimethylsilyl acetal (1) in the presence of a substoichiometric amount of chiral Lewis acid 2 or 3 provides the corresponding ~,a-difluom hydroxy esters 4-12 with high enantioselectivitles (up to 98% ee). Reaction temperature has a great influenc
β¦ LIBER β¦
A peptide-aluminum complex as a novel chiral Lewis acid. Asymmetric addition of cyanotrimethylsilane to aldehydes
β Scribed by Ohno, Hiroshi; Nitta, Hideaki; Tanaka, Kenzo; Mori, Atsunori; Inoue, Shohei
- Book ID
- 126141743
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 890 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3263
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## Abstract For Abstract see ChemInform Abstract in Full Text.