The first direct coupling of 1-trialkyls
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Ulla Halbes; Philippe Bertus; Patrick Pale
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Article
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2001
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Elsevier Science
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French
β 61 KB
1-Trialkylsilyl-1-alkynes can be directly coupled with vinyl triflates in the presence of TBAF, 3H 2 O and a catalytic amount of AgI and Pd(PPh 3 ) 4 . Functionalized enynes can thus be obtained in good to excellent yields without prior deprotection of the alkyne.