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A Pauson−Khand Approach to the Synthesis of Ingenol

✍ Scribed by Winkler, Jeffrey D.; Lee, Esther C. Y.; Nevels, LaToya I.


Book ID
124068395
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
75 KB
Volume
7
Category
Article
ISSN
1523-7060

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📜 SIMILAR VOLUMES


An intramolecular Pauson–Khand approach
✍ Ramon Rios; Albert Moyano; Miquel A Pericàs 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 98 KB

A procedure for the synthesis of chirally-substituted cyclopentadienes has been developed by employing the intramolecular Pauson-Khand reaction of chiral amides derived from 8-nonen-2-ynoic acid. Hydride-mediated reduction of the resulting cyclopentenone adducts followed by acid-catalysed dehydratio