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A One-Step Radical Synthesis of Pyrrol-2-acetic Acids.

✍ Scribed by Jeffrey H. Byers; Michael P. Duff; Gregory W. Woo


Publisher
John Wiley and Sons
Year
2003
Weight
71 KB
Volume
34
Category
Article
ISSN
0931-7597

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A one-step synthesis of [3-2H]oxazepam
✍ Dr. Shen K. Yang; Ziping Bao; Magang Shou πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 414 KB

## Abstract The proton at 3‐position of oxazepam (7‐chloro‐1,3‐dihydro‐3‐hydroxy‐5‐phenyl‐2__H__‐1,4‐benzodiazepin‐2‐one) undergoes a deuterium exchange in deuterated alkaline methanol. A base‐catalyzed keto‐enol tautomerism is proposed to be responsible for the observed deuterium exchange. This si