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A One Step General Synthesis of 3-Benzylcoumarins

โœ Scribed by Deshmukh, Sanjay Y. ;Kelkar, Shriniwas L. ;Wadia, Murzban S.


Book ID
120161622
Publisher
Taylor and Francis Group
Year
1990
Tongue
English
Weight
244 KB
Volume
20
Category
Article
ISSN
0039-7911

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## Abstract The proton at 3โ€position of oxazepam (7โ€chloroโ€1,3โ€dihydroโ€3โ€hydroxyโ€5โ€phenylโ€2__H__โ€1,4โ€benzodiazepinโ€2โ€one) undergoes a deuterium exchange in deuterated alkaline methanol. A baseโ€catalyzed ketoโ€enol tautomerism is proposed to be responsible for the observed deuterium exchange. This si