A one-pot synthesis of functionalized thiazoles from acid chlorides, secondary amines, ethyl bromopyruvate, and ammonium thiocyanate
β Scribed by Issa Yavari; Zinatossadat Hossaini; Maryam Sabbaghan; Majid Ghazanfarpour-Darjani
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 183 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1381-1991
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## Abstract An efficient synthesis of ethyl 2β(dimethylamino)β1,3βthiazoleβ4βcarboxylates is described __via__ a fourβcomponent reaction between acid chlorides, tetramethylthiourea, ethyl bromopyruvate, and ammonium thiocyanate.
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