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A One-Pot Synthesis of 1-Arylalka-1,3-diynes by Sequential Acetylene Zipper and Sonogashira Reactions.

✍ Scribed by Irina A. Balova; Svetlana N. Morozkina; David W. Knight; Sergei F. Vasilevsky


Publisher
John Wiley and Sons
Year
2003
Weight
116 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract A new class of spiro thiazolo[3,2‐__a__]pyrimidine compounds were synthesized by the one‐pot sequential 1,3‐dipolar cycloaddition of azomethine ylide (generated from isatin and sarcosine)–nitrile oxide to 2‐arylmethylidene‐6,7‐dihydro‐5__H__‐thiazolo[3,2‐__a__]pyrimidin‐3‐ones in modera