The characteristics of a phospholipid surface are of major importance in the activation of factor X in the presence of tissue factor-factor VIIa (TF-VIIa) complex. A possible tool which provides a measure of the surface corrugation and roughness is the fractal dimension analysis. This paper uses the
A numerical analysis of factor X activation in the presence of tissue factor-factor VIIa complex in a flow reactor
β Scribed by Srikant Gir; Steven M. Slack; Vincent T. Turitto
- Book ID
- 112817617
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 546 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0090-6964
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π SIMILAR VOLUMES
The effect of shear stress on the ability of tissue factorfactor VIIa complex to activate factor X in a continuous flow reactor was studied. Tissue factor immobilized in a phospholipid bilayer on the inner surface of a capillary tube was exposed to a perfusate containing factors VIIa and X flowing a
Development of a double exponential model for determining the intrinsic kinetic parameters for factor X activation by tissue factor-factor VIIa (TF:VIIa) complex, during the complete course of the reaction in a flow reactor is described. The model data reveal that the factor X activation rate consta