𝔖 Bobbio Scriptorium
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A novel technique for the production of hybrid antibodies

✍ Scribed by Thomas M. Moran; Osamu Usuba; Ely Shapiro; Leonard J. Rubenstein; Masafumi Ito; Constantin A. Bona


Book ID
118902087
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
611 KB
Volume
129
Category
Article
ISSN
0022-1759

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Mouse hybridoma cells were succesfully cultivated for more than 640 hours in the interparticle spaces of a tubular reactor packed with spherical dass beads. The maximum monoclonal antibody (MAb) concentration attained was 110 mg/l and a viable cell density in the order of 1 X 1 O7 cells/ml was achie