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A Novel Synthesis of N-Carboxydehydro-α-amino Acid Anhydrides and Their Reactions

✍ Scribed by Iwakura, Yoshio; Toda, Fujio; Torii, Yoshinori


Book ID
126857118
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
498 KB
Volume
31
Category
Article
ISSN
0022-3263

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Stepwise synthesis of oligopeptides with
✍ Oshio Iwakura; Keikichi Uno; Masanao Oya; Ryoichi Katakai 📂 Article 📅 1970 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 365 KB 👁 1 views

## Abstract Oligopeptides were synthesized in high yields by the controlled coupling reaction of __N__‐carboxy α‐amino acid anhydrides (NCA's) with amino acid and peptide sodium salts in the heterogeneous reaction medium of acetonitrile–water which contained sodium carbonate. In this solvent, it co