A novel synthesis of cyclopropyl lactam and amide from cis-2-aryl-3-benzoyl-1,1-dicynocyclopropane with H2O2 in the presence of NaHCO3
β Scribed by Zhongjiao Ren; Jie Chen; Yeying Lu; Danyi Wu; Weiguo Cao
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 289 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
Abstract
magnified image
The process for preparation of cyclopropyl lactam and amide from cisβ2βarylβ3βbenzoylβ1,1βdicynocyclopropane with H~2~O~2~ in the Presence of NaHCO~3~ is described. The highly stereoselective conversion of monocyano group to amide has been carried out in the present method.
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