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A Novel Synthesis of 2-Aminomethyl-1,3-butadienes from N,O-Acetals

✍ Scribed by Dipl.-Chem. Thomas Arenz; Priv.-Doz. Dr. Herbert Frauenrath


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
241 KB
Volume
29
Category
Article
ISSN
0044-8249

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Synthesis and CNS Activity of N,N-Disubs
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## Abstract Isatin and 5‐methylisatin were condensed with various aryloxyacetylhydrazides to furnish the 3‐(aryloxyacetylhydrazono)‐5‐alkylindolin‐2‐ones **1–4**. When **1–4** were subjected to __Mannich__ reaction, the __N,N__‐disubstituted 1‐(aminomethyl)‐5‐alkyl‐3‐(aryloxyacetylhydrazono)indolin