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A novel small molecule Met inhibitor, PF2362376, exhibits biological activity against osteosarcoma

✍ Scribed by A. T. Liao; J. McCleese; S. Kamerling; J. Christensen; C. A. London

Book ID
111220086
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
764 KB
Volume
5
Category
Article
ISSN
1476-5810

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## Abstract Osteosarcoma (OSA), the most common malignant bone tumor in dogs and children, exhibits a similar clinical presentation and molecular biology in both species. Unfortunately, 30–40% of children and 90% of dogs still die of disease despite aggressive therapy. The purpose of this study was