A novel silyl linker: Motif for side chain tethered approach to solid-phase glycopeptide synthesis

Solid-phase synthesis of dehydropeptide,

Solid-phase synthesis of dehydropeptide, AM-toxin II, using a novel selenyl linker by side-chain tethered strategy

✍ Eiji Horikawa; Masato Kodaka; Yoshiaki Nakahara; Hiroaki Okuno; Kazuhiko Nakamur 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 91 KB

The cyclic dehydrodepsipeptide, AM-toxin II, was efficiently synthesized by a solid-phase method using a novel selenyl linker. The cleavage from the resin with formation of a double bond is successfully achieved under mild oxidative conditions with TBHP.