๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A novel short and efficient asymmetric synthesis of statine analogues

โœ Scribed by Ralf M. Devant; Hans-E. Radunz

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
220 KB
Volume
29
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The statine analogues la_c have been obtained in high optical purity via addition of the chit-al acetate enolate 4 to the a-aminoaldehydes 5a_c, followed by transesterification.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of statine and its analogues b
Synthesis of statine and its analogues by homogeneous asymmetric hydrogenation
โœ T. Nishi; M. Kitamura; T. Ohkuma; R. Noyori ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 280 KB

Diastereoselective hydrogenation of N-protected y-amino fi-keto esters catalyzed by BINAP-Ru(II) complexes provides an efficient entry to the statine series with high enantiomeric purities.

A short and efficient asymmetric synthes
A short and efficient asymmetric synthesis of komaroviquinone
โœ Yutaka Suto; Kento Kaneko; Noriyuki Yamagiwa; Genji Iwasaki ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 286 KB

An asymmetric total synthesis of komaroviquinone (1), which is a natural product isolated from Dracocephalum komarovi and shows novel potent trypanocidal activity, was achieved in five steps from the known starting materials. The synthetic route is shorter and more efficient than the reported method