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A novel screen for nuclear mitochondrial gene associations with Parkinson’s disease

✍ Scribed by G. D. Mellick; P. A. Silburn; J. A. Prince; A. J. Brookes

Book ID
106206602
Publisher
Springer
Year
2004
Tongue
English
Weight
196 KB
Volume
111
Category
Article
ISSN
1435-1463

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.