In the course of our search for biologically active agents, we discovered a novel heterocyclizatinn reaction. We wish to report details of the reaction and then comment on possible mechanisms implicated in the cyclization. When an aqueous solution of 7-methyl-7-azabicycloL4.l.O]heptane (1) and 2 eq
A novel route to the triphenylene ring system by a triple intramolecular acyloin condensation
โ Scribed by Praefcke, Klaus ;Psaras, Panicos ;Bilgin, Belkiz
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1992
- Tongue
- English
- Weight
- 149 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0009-2940
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In contrast to their benzenoid counterparts, the reactions of fivemembered heterocyclic diazonium salts 1 have been comparatively little studied.
The finding that 1-benzyloxy-3-phenylureas undergo oxidative ring closures with lead tetraacetate in chloroform to l-benayloxybenzimidazolones In nearly quantitative yields (1) caused us to extend the study to other systems containing a readily oxidizable group situated y with respect to an aromatic
A novel Approach f o r t h e s y n t h e s i s of t h e BCD-ring system i n s t e r o i d s i s d e s c r i b e d . The sequence centers about t h e i n t r a m o l e c u l a r Diels-Alder r e a c t i o n of f u r a n 1 5 , which, depending on t h e r e a c t i o n c o n d i t i o n s , l e a d s pr
The Cyclopropylalkylidenecyclopropane Thermal Double Ring Expansion. A Novel Route to the Bicyclo[5.3.1]undecane Skeleton of the AB Ring System of Taxanes. -The mechanism of the reaction is explained by the initial formation of a diradical followed by opening to a homoallylic biradical which closes