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A novel protein, Romo1, induces ROS production in the mitochondria

✍ Scribed by Young Min Chung; Jun Suk Kim; Young Do Yoo

Book ID
116293234
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
743 KB
Volume
347
Category
Article
ISSN
0006-291X

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## Abstract HAP (a homologue of the ASY/Nogo-B protein), a novel human apoptosis-inducing protein, was found to be identical to RTN3. In an earlier study, we demonstrated that HAP localized exclusively to the endoplasmic reticulum (ER) and that its overexpression could induce cell apoptosis via a d