A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice
β Scribed by Benjamin Frydman; Carl W. Porter; Yulia Maxuitenko; Aparajita Sarkar; Subhra Bhattacharya; Aldonia Valasinas; Venodhar K. Reddy; Nick Kisiel; Laurence J. Marton; Hirak S. Basu
- Book ID
- 105991773
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 274 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0344-5704
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The effects of a new metalloproteinase inhibitor, BE 16627B [L-N-(N-hydroxy-2-isobutylsuccinynamoyl)-se~l-L-valine, M W 375.21 isolated from microbial cultures, on human tumor cell growth in nude mice were investigated. BEl6627B inhibited metalloproteinases in enzyme assays, as well as gelatinolysis