𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel one-step synthesis of 4H-furo[3,4-b]pyrans and a transformation into a difuro[3,4-b: 3′,4′-e]pyridine

✍ Scribed by Martín, Nazario ;Segura, José L. ;Seoane, Carlos ;Soto, José L. ;Morales, Margarita ;Suarez, Margarita

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
293 KB
Volume
1991
Category
Article
ISSN
0947-3440

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A simple one‐step synthesis of 2‐amino‐4‐aryl‐5‐oxo‐4__H__‐furo[3,4‐b]pyran‐3‐carbonitriles 7 is described. It involves reaction of 2,4(3__H__,5__H__)‐furandione (β‐tetronic acid) (5) with arylmethylenemalononitriles 4 in basic medium. Some substituent effects are noted and the assignments of ^13^C‐NMR spectra are discussed. Ring transformation of the furo[3,4‐b]pyran 7a leads to the difuro[3,4‐b:3′,4′‐e]pyridine 9.

📜 SIMILAR VOLUMES

Clean synthesis of furo[3,4-e]pyrazolo[3
Clean synthesis of furo[3,4-e]pyrazolo[3,4-b]pyridine-5-one derivatives in aqueous media
✍ Da-Qing Shi; Hao Yao 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 69 KB

## Abstract magnified image A series of 4‐aryl‐3‐methyl‐1‐phenyl‐7__H__‐furo[3,4‐__e__]pyrazolo[3,4‐__b__]pyridine‐5‐ones were synthesized __via__ the three‐component reaction of an aldehyde, 5‐amino‐3‐methyl‐1‐phenyl‐1__H__‐pyrazole and tetronic acid in aqueous media in the presence of triethylben