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A Novel One-Pot Synthesis of 3-Acetyl- and 3-Benzoylisoxazole Derivatives Using Ammonium Cerium Nitrate (CAN).

✍ Scribed by Ken-ichi Itoh; Shigeo Takahashi; Tetsuya Ueki; Takashi Sugiyama; T. Tomoyoshi Takahashi; C. Akira Horiuchi

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200251138

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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## Abstract magnified image A simple and highly efficient procedure for the Biginelli condensation reaction of aldehydes, β‐ketoesters, urea, or thiourea catalyzed by Ceric ammonium nitrate (CAN) as a Lewis‐acid at ambient temperature is described. The procedure proved to be simple and of high yiel