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A novel one-pot isocyanide-based four-component reaction: synthesis of highly functionalized 1H-pyrazolo[1,2-b]phthalazine-1,2-dicarboxylates and 1H-pyrazolo[1,2-a]pyridazine-1,2-dicarboxylates

✍ Scribed by Sajjad Keshipour; Salman Shojaei; Ahmad Shaabani


Book ID
116909513
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
510 KB
Volume
68
Category
Article
ISSN
0040-4020

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## Abstract The reactive 1 : 1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped with 4‐arylurazoles to produce the highly functionalized pyrazolo[1,2‐__a__][1,2,4]triazoles **5** in good yields (__Table__). The structures of the products