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A novel non-xanthine adenosine A1 receptor antagonist

โœ Scribed by Takao Terai; Yasuhiro Kita; Takahiro Kusunoki; Toshiko Shimazaki; Tsuyoshi Ando; Haruo Horiai; Atsushi Akahane; Youichi Shiokawa; Keizo Yoshida


Book ID
115890199
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
820 KB
Volume
279
Category
Article
ISSN
0014-2999

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ChemInform Abstract: Pilot-Scale Synthes
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Pilot-Scale Synthesis of a Novel Non-Xanthine Adenosine A 1 Receptor Antagonist. 1,3-Dipolar Cycloaddition of Pyridine N-Imine to an Acetylene. -A new, concise and efficient large scale procedure for the preparation of title compound FK838 (VII) is developed. It is based on a detailed investigation