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A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis

✍ Scribed by M. Slee; J. Finkemeyer; M. Krupa; R. Raghupathi; J. Gardner; P. Blumbergs; M. Agzarian; D. Thyagarajan


Book ID
116676136
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
977 KB
Volume
18
Category
Article
ISSN
0967-5868

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Chronic progressive external ophthalmopl
✍ Thomas GrΓΌnewald; Hildburg Porschke; Hans Goebel; Heinz Reichmann; Peter Seibel πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 576 KB

Large-scale deletions and point mutations of the mitochondrial DNA are generally accepted as being involved in the pathogenesis of diseases associated with mitochondrial encephalomyopathies such as Kearns-Sayre syndrome and chronic progressive external ophthalmoplegia (CPEO). We screened suspected p