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Multiple deletions of mitochondrial DNA in muscle from a patient with benign progressive external ophthalmoplegia

✍ Scribed by Y. Campos; M. A. Martín; J. C. Rubio; C. Ricard; A. Cabello; J. Arenas


Publisher
Springer
Year
1996
Tongue
English
Weight
164 KB
Volume
19
Category
Article
ISSN
0141-8955

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Chronic progressive external ophthalmopl
✍ Thomas Grünewald; Hildburg Porschke; Hans Goebel; Heinz Reichmann; Peter Seibel 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

Large-scale deletions and point mutations of the mitochondrial DNA are generally accepted as being involved in the pathogenesis of diseases associated with mitochondrial encephalomyopathies such as Kearns-Sayre syndrome and chronic progressive external ophthalmoplegia (CPEO). We screened suspected p