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A novel method for the 1,2-carbonyl transposition of pleuromutilins

✍ Scribed by Céline Duquenne; Timothy F. Gallagher; Jeffrey M. Axten

Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
197 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new and efficient 1,2-carbonyl transposition procedure for the formation of 2-keto pleuromutilin compounds is described. The synthetic sequence is performed in four steps and 26% overall yield.

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