Synthesis of 2-tetralones via a novel 1,2-carbonyl transposition of 1-tetralones
β Scribed by David C Pryde; Steven S Henry; A.I Meyers
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 175 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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The dynamic kinetic resolution of 2-aroyl-1-tetralones was achieved via asymmetric transfer hydrogenation using (S,S)-RuCl(p-cymene)TsDPEN (TsDPEN οΌ N-(tosyl)-1,2-diphenylethylenediamine) in formic acid/triethylamine (5βΆ2, molar ratio), afforded the desired products in good yields (up to 85%) with d