Daunomyclnone Za has been synthesized by a novel reglo-and stereoselectlve route that establishes the tetracvclic framework and the C-7 oxveen m .Y naphthacenol 5c via a double Frledel-Crafts acylatlon -
✦ LIBER ✦
A novel method for regio- and stereoselective hydroxylation of anthracycline glycosides
✍ Scribed by Shohachi Nakajima; Hiroyuki Kawai; Masayuki Sakakibara; Kuniaki Tatsuta; Noboru Ōtake
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 114 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Hydroxylation at C-10 position of anthracycline glycoside proceeds stereoselectively with trimathylamine-N-oxide in DMF.
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