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A novel method for peptide block synthesis using unprotected peptides

✍ Scribed by Yasushi Ishihama; Osamu Ito; Yoshiya Oda; Tatsuyuki Takenawa; Masahiro Iwakura


Book ID
104261288
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
218 KB
Volume
40
Category
Article
ISSN
0040-4039

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✍ Youhei Sohma; Atsuhiko Taniguchi; Taku Yoshiya; Yousuke Chiyomori; Fukue Fukao; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB

## Abstract After over a decade of studies on aspartic protease inhibitors and water‐soluble prodrugs, we have been developing a novel method, since 2003, called ‘__O__‐acyl isopeptide method’, for the synthesis of peptides containing difficult sequences. With our recent discoveries of ‘__O__‐acyl