A novel isoflavone from the stems of Ageratum conyzoides
β Scribed by R.N. Yadava; Saurabh Kumar
- Book ID
- 114243626
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 69 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0367-326X
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The water soluble fraction of Ageratum conyzoides L. (WSF) was studied in isolated rat uterus and intestinal smooth muscles in order to evaluate its popular use as a spasmolytic. WSF (0.2 and 0.4 mg/mL) increased EC 50 values and decreased maximum responses to acetylcholine and calcium chloride. WSF
An extract obtained from the leaves of Ageratum conyzoides L. changed the electrocardiogram, atrial impulse velocity, and coronary vessels resistance on isolated guinea-pig heart. Electrocardiographic alterations were: (a) PR interval increased from 80 AE 1.4 ms to 105 AE 14 ms (p `0.01); (b) QT int