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A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1

✍ Scribed by Richa Basundra; Akinchan Kumar; Samir Amrane; Anjali Verma; Anh Tuân Phan; Shantanu Chowdhury


Book ID
111313651
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
534 KB
Volume
277
Category
Article
ISSN
1432-1327

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Expression of thymidine kinase (TK) gene in normal human diploid cells is both cell cycle and age dependent and appears to be transcriptionally regulated. Several studies have indicated that the G I /S control sequence may reside within the region of about 130 bp upstream of the transcription initia