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A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies

✍ Scribed by Mohamed A Elrayess; Karen E Webb; David M Flavell; Mikko Syvänne; Marja-Riitta Taskinen; M.Heikki Frick; Markku S Nieminen; Y.Antero Kesäniemi; Amos Pasternack; J.Wouter Jukema; John J.P Kastelein; Aeilko H Zwinderman; Steve E Humphries


Book ID
119435837
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
222 KB
Volume
168
Category
Article
ISSN
0021-9150

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## Abstract The prodynorphin gene (__PDYN__) encoding the anticonvulsant peptide dynorphin is a strong candidate for a seizure suppressor gene and thus a possible modulator of susceptibility to temporal lobe epilepsy. We performed a case control association study in 155 patients with nonlesional te