𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel Fmoc-based anchorage for the synthesis of protected peptides on solid phase

✍ Scribed by LIU, YIN-ZENG ;DING, SHAO-HUA ;CHU, JI-YU ;FELIX, ARTHUR M.

Book ID
115099033
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
386 KB
Volume
35
Category
Article
ISSN
0367-8377

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Protection of 3,4-dihydroxyphenylalanine
Protection of 3,4-dihydroxyphenylalanine (DOPA) for Fmoc solid-phase peptide synthesis
✍ Bi-Huang Hu; Phillip B Messersmith πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 110 KB

Cyclic ethyl orthoformate (Ceof) was utilized as a protecting group to protect the catechol hydroxyl groups of 3,4-dihydroxyphenylalanine (DOPA). This protecting group is stable to strong bases and nucleophiles, and can be removed eciently by 1 M trimethylsilyl bromide in triΒ―uoroacetic acid in the

Improved acidolytic deprotection conditi
Improved acidolytic deprotection conditions for the Fmoc-based solid-phase synthesis of thioxo peptides
✍ Julia H Miwa; Laura A Margarida; Ann E Meyer πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 62 KB

The acid-mediated cleavage of a synthetic thioxo peptide was monitored using deprotection cocktails with varying concentrations of TFA. Thioxo peptides are acid labile, undergoing cleavage at the amide linkage immediately following the thioamide linkage in the sequence. This acid lability makes Fmoc