𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel fluorous palladium catalyst for Heck reaction in a fluorous biphase system (FBS)

✍ Scribed by Wen-Bin Yi; Chun Cai; Xin Wang

Book ID
103834713
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
202 KB
Volume
274
Category
Article
ISSN
1381-1169

No coin nor oath required. For personal study only.

✦ Synopsis

Palladium(II) perfluorooctanesulfonate [Pd(OSO 2 R f8 ) 2 ] catalyses the highly efficient Heck reaction in the presence of a catalytic amount of a perfluoroalkylated-pyridine as a ligand in a fluorous biphase system (FBS) composed of toluene and perfluorodecalin. The fluorous phase containing the active palladium species is easily separated and can be reused several times without a significant loss of catalytic activity.

πŸ“œ SIMILAR VOLUMES

Bimetallic catalytic cascade ring closin
Bimetallic catalytic cascade ring closing metathesisβ€”intramolecular Heck reactions using a fluorous biphasic solvent system or a polymer-supported palladium catalyst
✍ Ronald Grigg; Mark York πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 164 KB

The combination of ring closing metathesis and intramolecular Heck reactions in a cascade gives bridged ring systems in good yield. Two methods using either a Β―uorous biphasic solvent system or a polymersupported palladium catalyst overcome the observed incompatibility of the catalysts.