Bimetallic catalytic cascade ring closing metathesis—intramolecular Heck reactions using a fluorous biphasic solvent system or a polymer-supported palladium catalyst

✍ Scribed by Ronald Grigg; Mark York

• Book ID: 104210810
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 164 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01250-8

✦ Synopsis

The combination of ring closing metathesis and intramolecular Heck reactions in a cascade gives bridged ring systems in good yield. Two methods using either a ¯uorous biphasic solvent system or a polymersupported palladium catalyst overcome the observed incompatibility of the catalysts.