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A novel fluorescent α-conotoxin for the study of α7 nicotinic acetylcholine receptors

✍ Scribed by Arik J. Hone; Paul Whiteaker; Sean Christensen; Yingxian Xiao; Erin L. Meyer; J. Michael McIntosh

Book ID
111755816
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
439 KB
Volume
111
Category
Article
ISSN
0022-3042

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## Abstract α‐Conotoxins, from cone snails, and α‐neurotoxins, from snakes, are competitive inhibitors of nicotinic acetylcholine receptors (nAChRs) that have overlapping binding sites in the ACh binding pocket. These disulphide‐rich peptides are used extensively as tools to localize and pharmacolo