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A novel family of linkages for advanced motion synthesis

✍ Scribed by Chao Chen; Jorge Angeles

Book ID
108206480
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
327 KB
Volume
43
Category
Article
ISSN
0094-114X

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A novel solid phase synthesis of 3'-phosphorylated oligonuclcotides is described. The chain assembly is carried out by phosphoramidite strategy on solid support 2, which allows a mild and fast release of the oligonueleotide in solution. The applicability of the method is demonstrated by preparation