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A Novel Dipeptide-Based HIV Protease Inhibitor Containing Allophenylnorstatine.

โœ Scribed by Hamdy M. Abdel-Rahman; Nawal A. El-Koussi; Gamal S. Alkaramany; Adel F. Youssef; Yoshiaki Kiso


Publisher
John Wiley and Sons
Year
2005
Weight
14 KB
Volume
36
Category
Article
ISSN
0931-7597

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โœ Yoshiaki Kiso; Hikaru Matsumoto; Sota Mizumoto; Tooru Kimura; Yoichi Fujiwara; K ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 312 KB ๐Ÿ‘ 1 views

The human immunodeficiency virus (HIV) codes for an aspartic protease known to be essential for retroviral maturation and replication. HIV protease is formed from two identical 99 amino acid peptides. We synthesized [(NHCH 2 CH 2 -S-CH 2 CO) [51][52] , Ala 67,95 ]HIV-1 protease using the thioether c