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A novel cyclization reaction of oxidodiazoalkanes: formation of pyrazoles and pyridazines

✍ Scribed by Toshiro Harada; Eiji Akiba; Akira Oku


Book ID
104222363
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
133 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis


The thermal decomposition of dialkali metal salts of 8-and rhydroxyketone tosylhydrazones in refluxing DME produced pyrazoles and pyridazines, respectively.


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Regioselective synthesis of some novel p
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The latter compound reacts regioselectively with some nitrilimines and nitrile oxides to afford the corresponding pyrazole and isoxazole derivatives, respectively. These reaction products react with hydrazine hydrate to give the novel pyrazolo [3,4-d]pyridazine and isoxazolo [3,4-d]pyridazine deriva