A novel cyclization reaction of oxidodiazoalkanes: formation of pyrazoles and pyridazines
β Scribed by Toshiro Harada; Eiji Akiba; Akira Oku
- Book ID
- 104222363
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 133 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The thermal decomposition of dialkali metal salts of 8-and rhydroxyketone tosylhydrazones in refluxing DME produced pyrazoles and pyridazines, respectively.
π SIMILAR VOLUMES
The thermal decomposition of dialkali metal salts of &-hydroxybutyl ketone and s-hydroxypentyl ketone tosylhydrazones in diglyme at 80-120 OC produced the l-
The latter compound reacts regioselectively with some nitrilimines and nitrile oxides to afford the corresponding pyrazole and isoxazole derivatives, respectively. These reaction products react with hydrazine hydrate to give the novel pyrazolo [3,4-d]pyridazine and isoxazolo [3,4-d]pyridazine deriva