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A novel class of fluorinated cinchona alkaloids as surface modifiers for the enantioselective heterogeneous hydrogenation of α-ketoesters

✍ Scribed by Cecilia Mondelli; Christoph Bucher; Alfons Baiker; Ryan Gilmour


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
241 KB
Volume
327
Category
Article
ISSN
1381-1169

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The enantioselective hydrogenations of ethyl pyruvate (EP), methyl benzoylformate (MBF), ketopantolactone (KPL) and pyruvaldehyde dimethylacetal (PADA) were studied on Pt-alumina catalyst modified by a new modifier namely ␣-isoquinine (␣-IQ) with rigid conformation and for comparison by quinine (Q)