A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-Benzothiazepines
β Scribed by Michael B. Tollefson; Stephen A. Kolodziej; Theresa R. Fletcher; William F. Vernier; Judith A. Beaudry; Bradley T. Keller; David B. Reitz
- Book ID
- 108073068
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 144 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0960-894X
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π SIMILAR VOLUMES
A series of 2,3-disubstituted-4-phenylquinolines were prepared and were found to inhibit the apical sodium co-dependent bile acid transporter (ASBT). Alkyl and ester substitution at the 3-position showed comparable activities while substitution at the 2-position was much more sensitive to the nature
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