A Novel Bis-Thiourea Organocatalyst for the Asymmetric Aza-Henry Reaction
✍ Scribed by Constantinos Rampalakos; William D. Wulff
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 287 KB
- Volume
- 350
- Category
- Article
- ISSN
- 1615-4150
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📜 SIMILAR VOLUMES
## Abstract Novel bifunctional catalysts having guanidine and thiourea functional groups were developed for the asymmetric Henry (nitroaldol) reaction. Various structural developments of the catalyst revealed that the compound having an octadecyl‐substituted guanidine and thiourea groups linked wit
## Abstract A new kind of bifunctional (thio)urea‐phosphine catalyst was synthesized and applied to the aza‐Morita–Baylis–Hillman reaction of __N__‐sulfonated imines with methyl vinyl ketone, phenyl vinyl ketone, ethyl vinyl ketone or acrolein. Moderate to excellent __ee__ and yields of the product