A novel autoantibody to eosinophil peroxidase in patients with primary biliary cirrhosis
โ Scribed by Ohira, Hiromasa; Takiguchi, Junko; Rai, Tsuyoshi; Abe, Kazumichi; Takeda, Junko; Shishido, Shoichiro; Sato, Yukio
- Book ID
- 122588850
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 173 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0016-5085
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๐ SIMILAR VOLUMES
Eosinophilia is a distinctive feature of primary biliary cirrhosis (PBC), especially in its early stages. Intriguingly, treatment with ursodeoxycholic acid (UDCA) ameliorates eosinophilia as well as liver tests in patients with PBC. It remains unknown, however, whether eosinophils in PBC patients ar
develop thrombocytopenia of various causes, e.g., decreased controls for the indirect and direct MAIPA assay, respectively, and production, increased turnover or splenic ''pooling.'' were obtained from healthy donors of blood group AB. The specificity of the antibodies was further determined by the
AFTAB ANSAKI,' Ross L. cOk>i)E12,' AND M. ERIC GERSHWIN' Primary biliary cirrhosis (PBC) is an autoimmune disease of liver associated with a unique serologic response to mitochondrial autoantigens. Many of the autoantigens recognized by autoantibodies in PBC are members of the 2-0x0-acid dehydrogena