A Novel Asymmetric Benzoin Reaction Catalyzed by a Chiral Triazolium Salt. Preliminary communication

✍ Scribed by Dieter Enders; Klaus Breuer; J. Henrique Teles

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: German
• Weight: 225 KB
• Volume: 79
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19960790427

✦ Synopsis

Abstract

Using the chiral triazolium salt 1 as catalyst, a novel asymmetric variant of the benzoin reaction is reported. For the first time, the scope of the method is extended to a broader range of aromatic aldehydes 2, affording the acyloins 3a–h in yields of 22–72% and enantiomeric excesses up to 86%.