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A Novel Approach To the Synthesis of Chiral Terminal 1,2-Diamines

โœ Scribed by Markidis, Theodoros; Kokotos, George

Book ID
111909107
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
79 KB
Volume
66
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES

Aziridinium ions from phenylglycinol โ€” A
Aziridinium ions from phenylglycinol โ€” A new approach to the synthesis of chiral diamines
โœ Simon E de Sousa; Peter O'Brien ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 254 KB

A new two-step method [(i) N,N-dialkylation; (ii) aziridinium ion formation followed by amine attack] for the synthesis of chiral diamines from phenylglycinol is described. The two steps can be carried out sequentially without isolation of the intermediate amino alcohols to give diamines in good yie