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A Novel Approach to the Synthesis of Bicyclic Lactones via an Interrupted Nazarov Reaction of gem-Divinyl Dihydrofurans.

✍ Scribed by Vijay Nair; S. Bindu; V. Sreekumar; Angele Chiaroni


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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Toward a novel approach to bis-Ξ²-lactam
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## Abstract magnified image A facile synthesis of bis‐β‐lactams has been executed using chloromethylenedimethylammonium chloride (Vilsmeier reagent), prepared easily from __N__,__N__‐dimethylformamide and phosphorus oxychloride. It works out as a versatile acid activator reagent for the direct [2 +