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A Novel Approach to Oligonucleotide Synthesis Using an Imidazolium Ion Tag as a Soluble Support.

✍ Scribed by Robert A. Donga; Syed M. Khaliq-Uz-Zaman; Tak-Hang Chan; Masad J. Damha


Publisher
John Wiley and Sons
Year
2007
Weight
14 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract magnified image A facile synthesis of bis‐β‐lactams has been executed using chloromethylenedimethylammonium chloride (Vilsmeier reagent), prepared easily from __N__,__N__‐dimethylformamide and phosphorus oxychloride. It works out as a versatile acid activator reagent for the direct [2 +