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A novel approach for total synthesis of cryptophycins via asymmetric crotylboration protocol

โœ Scribed by Ulhas P. Dhokte; Vien V. Khau; Darrell R. Hutchison; Michael J. Martinelli


Book ID
104260190
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
226 KB
Volume
39
Category
Article
ISSN
0040-4039

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ChemInform Abstract: A Novel Approach fo
โœ U. P. DHOKTE; V. V. KHAU; D. R. HUTCHISON; M. J. MARTINELLI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 2 views

A Novel Approach for Total Synthesis of Cryptophycins via Asymmetric Crotylboration Protocol. -Crotylboration of aldehyde (I) with the ฮฑ-pinene-derived boron reagent (II) provides the optically pure alcohol (IV) after oxidative work-up. Compound (IV) is linearly converted to the fragment A (V) of th